[Plasmocytic lymphoma/multiple myeloma. Association or transformation?]

Extramedullary plsmocytoma (plasmocytic lymphoma) is very rare, it seems to have an indolent course and the progression to a multiple myeloma is very rare (about 30 cases are reported in the literature). We report the case of 68-old-woman who presented in 1997 with an axillary left node. Physical examination, biologic and radiologic tests were normal. The histologic examination (of this mass) revealed a primary extramedullary plasmocytoma. She was treated with the combination of chemiotherapy and radiotherapy. 18 months later, at the follow up, the patient developed an Ig A lambda multiple myeloma. She was treated by chemiotherapy with favorable course.