Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Wormy mice in a hybrid zone.

R D Sage1, D Heyneman, K C Lim

  • 1Department of Biochemistry and Museum of Vertebrate Zoology, University of California, Berkeley, California 94720, USA.

Nature
|November 6, 1986
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Laser-free trapped-ion entangling gates with simultaneous insensitivity to qubit and motional decoherence.

Physical review. A·2026
Same author

Evaluating Bacillus flexus as bioremediators for ammonia removal in shrimp culture water and wastewater and characterizing microbial communities in shrimp pond sludge.

Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]·2024
Same author

Clinical and radiological outcomes of SARS-CoV-2 related organising pneumonia in COVID-19 survivors.

The Medical journal of Malaysia·2023
Same author

Gastrointestinal: Cholangiocarcinoma with Strongyloides stercoralis infestation.

Journal of gastroenterology and hepatology·2022
Same author

High-fidelity laser-free universal control of trapped ion qubits.

Nature·2021
Same author

Quantum Logic Spectroscopy with Ions in Thermal Motion.

Physical review. X·2021
Same journal

Family of magnetic field-boosted superconductors in rhombohedral graphene.

Nature·2026
Same journal

What's the human cost of US research turmoil? A new film finds out.

Nature·2026
Same journal

Daily briefing: Ovaries start a second job after menopause.

Nature·2026
Same journal

Audio long read: Is the peptide craze backed by science? The promise behind the hype.

Nature·2026
Same journal

Scientists fight back against far-right plans to restrict academic freedom in Germany.

Nature·2026
Same journal

How AI can crack open the 'hidden curriculum' for neurodivergent students.

Nature·2026
See all related articles

Hybrid mouse populations exhibit significantly higher parasitic worm loads, suggesting reduced fitness and acting as a genetic barrier between species. This indicates potential gene flow disruption due to hybrid susceptibility.

Area of Science:

  • Genetics
  • Parasitology
  • Evolutionary Biology

Background:

  • Studying genetic barriers between species is crucial for understanding speciation.
  • Hybrid zones offer unique opportunities to investigate genetic incompatibilities and fitness.
  • Parasitic infections can significantly impact host fitness and reproductive success.

Purpose of the Study:

  • To analyze the genetic barriers between Mus musculus and Mus domesticus.
  • To investigate the role of parasitic worm loads in hybrid mouse populations.
  • To determine if hybrid susceptibility to parasites contributes to reduced fitness.

Main Methods:

  • Examined parasitic worm (pinworms, nematodes, tapeworms) burdens in two mouse species and their natural hybrids.
  • Analyzed mice from a narrow hybridization zone in southern Germany.

Related Experiment Videos

  • Compared parasite loads in hybrid mice to those in pure species populations.

    • Main Results:

    • Mice within the hybridization zone exhibited disproportionately high numbers of pinworms (over 500 per gut) compared to controls (mean of 40 per gut).
    • Other nematodes and tapeworms also showed non-random, excessive distributions in hybrid zone mice.
    • These findings suggest hybrid mice are unusually susceptible to parasitism.

    Conclusions:

    • Hybrid populations may have reduced fitness due to genetic incompatibilities affecting parasite resistance.
    • Hybrid zones can act as genetic sinks, hindering gene flow between parent species.
    • Environmental factors within the hybrid zone do not appear to be the primary cause of increased infection rates.