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Published on: February 8, 2019
Influenza vaccination induced leukocytoclastic vasculitis and pauci-immune crescentic glomerulonephritis
N Yanai-Berar1, O Ben-Itzhak, J Gree
1Department of Nephrology, Rambam Medical Center, Haifa, Israel.
Abstract:
Influenza vaccination is a widely accepted practice, particularly among the elderly and high-risk individuals. Minor and transitory side effects following the vaccination are common, while systemic complications are infrequently reported. We describe here a case of a patient who presented to the emergency room with arthralgia, myalgias and purpura, following influenza vaccination. Necrotizing vasculitis associated with pauci-immune glomerulonephritis was observed on kidney biopsy. With increasing use of influenza vaccination, attention should be drawn to the possible expression of systemic adverse effects such as vasculitis and glomerulonephritis.
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