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Diffuse large B-cell lymphoma with fibrillary matrix
Jean-Louis Dargent1, Isabelle Meiers, Laurence Lespagnard
1Laboratoire d'Anatomie Pathologique, CHU Saint-Pierre/Institut Jules Bordet, Université Libre de Bruxelles, Brussels, Belgium. jldargent@hotmail.com
Abstract:
Diffuse large B-cell lymphoma (DLBCL) with fibrillary matrix is an extremely rare variant of non-Hodgkin's lymphoma (NHL) whose pathological features are poorly known. Here, we report on our experience with such a condition arising in a 71-yr-old woman. Our findings not only demonstrate that DLBCL with fibrillary matrix actually represents a peculiar subtype of DLBCL, but they also illustrate that the cytologic and flow cytometric features in this disorder can be deceptive enough as to mislead even the most experienced cytopathologist.