Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Smoking cessation in methadone maintenance.

Steve Shoptaw1, Erin Rotheram-Fuller, Xiaowei Yang

  • 1Friends Research Institute, Los Angeles, CA, UCLA, Department of Psychiatry, Los Angeles, CA 90025, USA. shoptaw@friendsresearch.org

Addiction (Abingdon, England)
|October 3, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Perceptions of Buprenorphine With Naloxone Treatment and the Fear of Precipitated Withdrawal: A Qualitative Exploration With HIV Prevention Trials Network 094 INTEGRA Participants and Staff.

Drug and alcohol review·2026
Same author

Cost-effectiveness of contingency management for methamphetamine use disorder: A model-based analysis.

Addiction (Abingdon, England)·2026
Same author

Safety of Intravenous Methamphetamine in Patients Taking Mirtazapine: A Two-Site Phase 1b Randomized Controlled Trial.

Journal of clinical psychopharmacology·2026
Same author

Integrating HIV and Stimulant-Use Disorder Treatment: A Pilot Implementation Effectiveness Trial of Contingency Management in HIV Care.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
Same author

One in 4 transplant hepatologists in the United States screens positive for unhealthy alcohol use.

Hepatology communications·2025
Same author

Understanding Perceived Pill Burden in Older Adults with HIV: Exploring Clinical and Demographic Determinants.

AIDS and behavior·2025

Contingency management significantly improved smoking cessation during nicotine replacement therapy for methadone-maintained smokers. However, long-term smoking cessation effects were not sustained, though reductions in illicit drug use were noted.

Area of Science:

  • Addiction Medicine
  • Public Health
  • Pharmacology

Background:

  • Tobacco smoking is prevalent among individuals undergoing treatment for opiate dependence.
  • Nicotine replacement therapy (NRT) is a common tool for smoking cessation.
  • Optimizing cessation strategies for this population is crucial for overall health outcomes.

Purpose of the Study:

  • To assess the efficacy of relapse prevention and contingency management interventions in enhancing smoking cessation outcomes.
  • To evaluate these interventions when combined with nicotine replacement therapy in methadone-maintained smokers.

Main Methods:

  • An experimental 2x2 factorial repeated measures design was employed.
  • 175 participants received NRT for 12 weeks, randomized into four groups: patch-only, relapse prevention + patch, contingency management + patch, or both interventions + patch.

Related Experiment Videos

  • Smoking abstinence was assessed via carbon monoxide breath and urine tests, alongside self-reported smoking rates.

    • Main Results:

    • Contingency management significantly increased smoking abstinence rates during the 12-week treatment period (P=0.0003).
    • Relapse prevention did not show a significant effect on smoking abstinence.
    • No significant differences in smoking cessation were observed at 6- and 12-month follow-ups.
    • Participants achieving smoking abstinence also showed significant reductions in illicit opiate and cocaine use.

    Conclusions:

    • Contingency management, when used with NRT, effectively optimizes smoking cessation during opiate dependence treatment.
    • While short-term gains are evident, long-term smoking cessation maintenance requires further investigation.
    • A strong association exists between reduced cigarette smoking and reduced illicit substance use in this population.