Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Histopathological grading does not affect survival after R0 surgery for gastric cancer.

K Inoue1, Y Nakane, T Michiura

  • 1Second Department of Surgery, Kansai Medical University, Osaka, Japan. inoueke@takii.kmu.ac.jp

European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
|October 3, 2002
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The effect of lipid content on virtual non-contrast images and iodine density estimation from dual-layer spectral computed tomography: A phantom study.

Radiography (London, England : 1995)·2026
Same author

Effects of scan parameters on the accuracies of iodine quantification and hounsfield unit values in dual layer dual-energy head and neck computed tomography: A phantom study conducted in a hospital in Japan.

Radiography (London, England : 1995)·2023
Same author

Comparisons of the Effects of Dietary Fats on Serum and Liver Lipid Levels of Rats.

Bioscience, biotechnology, and biochemistry·2016
Same author

Anal canal duplication in childhood.

Pediatric surgery international·2013
Same author

Immunohistochemical profile of phyllodes tumors of the breast.

Oncology reports·2011
Same author

Expression and localization of matrix metalloproteinases and tissue inhibitors of metalloproteinases as a prognostic factor in advanced colorectal carcinomas.

Oncology reports·2011

Histopathological Grading impacts R0 resection rates in gastric cancer surgery, but does not independently affect patient survival. This study analyzed 1455 gastric adenocarcinoma patients undergoing resection.

Area of Science:

  • Oncology
  • Surgical Pathology
  • Cancer Research

Background:

  • Gastric cancer resection outcomes are influenced by various factors.
  • The prognostic role of histopathological grading requires further clarification.
  • Accurate staging is crucial for predicting patient survival after gastric cancer surgery.

Purpose of the Study:

  • To determine if histopathological grading (UICC, TNM Classification) impacts survival rates following gastric cancer resection.
  • To investigate the prognostic significance of histopathological grading in gastric adenocarcinoma patients.

Main Methods:

  • Retrospective review of 1455 patients with gastric adenocarcinoma who underwent gastrectomy.
  • Analysis of R0, R1, and R2 resection rates based on histopathological grade.

Related Experiment Videos

  • Multivariate analysis to assess the independent prognostic value of grading in R0 resection cases.

    • Main Results:

    • R0 resection rates decreased with increasing histopathological grade (Grade 1: 86.5%, Grade 2: 79.7%, Grade 3: 69.2%).
    • R1 and R2 resection rates increased with higher grades.
    • Histopathological grading did not significantly influence survival in patients who achieved R0 resection (n=1119).

    Conclusions:

    • UICC Histopathological Grading is associated with R0 resection rates in gastric cancer.
    • Histopathological Grading is not an independent prognostic factor for survival after R0 resection for gastric cancer.