[Early criteria for the diagnosis of chronic carbon monoxide exposure]

A clinico-laboratory study is carried out on 100 workers from the coke-chemical plant "Mining Complex Kremikovtzy", exposed to chronic effect of carbon oxide, at concentrations close to MAC. A wide range of laboratory indicators are employed for the purpose: hematologic, biochemical and enzymatic. Increased alkaline phosphatase and aldolase activity, increased fibrinogen values and leucineaminopeptidase inhibition are pointed out as being most demonstrative of the early carbon oxide effects on the organism.