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Updated: Aug 14, 2026

An “All-laser” Endothelial Transplant
Published on: July 6, 2015
Biomechanics of the cornea and wavefront-guided laser refractive surgery
1Department of Ophthalmology, Biomedical Engineering Center, The Ohio State University, Columbus 43210, USA. Roberts.8@osu.edu
Purpose:
Wavefront-guided laser refractive surgery induces postoperative optical aberrations that are not explained by the ablation profile.
Methods:
A conceptual model is presented for a potential mechanism of surgically-induced corneal shape change that is dependent on structural modification, rather than ablation profile.
Results:
Examples are provided from clinical and basic studies that are consistent with the proposed model.
Conclusion:
Corneal biomechanical response to ablative surgery may significantly affect outcomes, and should be taken into account when planning customized procedures.

