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[E selectin of blood in patients with unstable angina pectoris]
Ewa Grabarczyk1, Teresa Wodyńska, Ryszard Paczuski
1Katedra i Zakład Patofizjologii Akademii Medycznej im. L. Rydygiera w Bydgoszczy.
Adhesive molecules released from cellular surface, detected in body blood and liquids were determined as soluble or circulatory. In immunologically inflammatory process resulting from endothelium damage E-selectin is undoubtedly involved. The aim of this investigation was the concentration assessment of soluble E-selectin in blood serum in patients suffering from unstable angina pectoris. The expanding atheramotous process may bring about vascular endothelium dysfunction. In blood serum with citrate of 94 angina pectoris patients one found statistically higher E-selectin concentration than in control group. On the other hand, no statistically relevant differences were found pertaining to coexistent risk factors such as: high level of cholesterol in blood serum, hypertension, diabetes mellitus or smoking. Increased concentration was not age related. E-selectin was determined in citrate blood serum by ELISA immunoenzymatic method using Bender Medsystems kit.
Adhesive molecules released from cellular surface, detected in body blood and liquids were determined as soluble or circulatory. In immunologically inflammatory process resulting from endothelium damage E-selectin is undoubtedly involved. The aim of this investigation was the concentration assessment of soluble E-selectin in blood serum in patients suffering from unstable angina pectoris. The expanding atheramotous process may bring about vascular endothelium dysfunction. In blood serum with citrate of 94 angina pectoris patients one found statistically higher E-selectin concentration than in control group. On the other hand, no statistically relevant differences were found pertaining to coexistent risk factors such as: high level of cholesterol in blood serum, hypertension, diabetes mellitus or smoking. Increased concentration was not age related. E-selectin was determined in citrate blood serum by ELISA immunoenzymatic method using Bender Medsystems kit.