Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Drug resistant tuberculosis.

Stephan L Kamholz1

  • 1Department of Medicine, North Shore University Hospital, 300 Community Drive, Manhasset, NY 11030, USA.

Journal of the Association for Academic Minority Physicians : the Official Publication of the Association for Academic Minority Physicians
|October 5, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

National Trends in Incidence and Outcomes of Patients With Heart Failure Requiring Respiratory Support.

The American journal of cardiology·2019
Same author

Isolated Pulmonic Valve Endocarditis.

The American journal of case reports·2019
Same author

Results of a Quality Improvement Project Aimed at Eliminating Healthcare Waste by Changing Medical Resident Test Ordering Behavior.

Journal of clinical medicine research·2017
Same author

Wine, spirits and the lung: good, bad or indifferent?

Transactions of the American Clinical and Climatological Association·2008
Same author

Pulmonary and cardiovascular consequences of smoking.

Clinics in occupational and environmental medicine·2006
Same author

Ventilator strategy for status asthmaticus in pregnancy: a case-based review.

The Journal of asthma : official journal of the Association for the Care of Asthma·2005
Same journal

Is repeat endoscopy necessary after percutaneous endoscopic gastrostomy?

Journal of the Association for Academic Minority Physicians : the official publication of the Association for Academic Minority Physicians·2002
Same journal

AIDS and Islam in America.

Journal of the Association for Academic Minority Physicians : the official publication of the Association for Academic Minority Physicians·2002
Same journal

Promoting identification of HIV-infected youths: borrowing concepts from the media to reduce the HIV epidemic?

Journal of the Association for Academic Minority Physicians : the official publication of the Association for Academic Minority Physicians·2002
Same journal

Health disparities research--a model for conducting research on cancer disparities: characterization and reduction.

Journal of the Association for Academic Minority Physicians : the official publication of the Association for Academic Minority Physicians·2002
Same journal

Adiposity changes in youth with a family history of cardiovascular disease: impact of ethnicity, gender and socioeconomic status.

Journal of the Association for Academic Minority Physicians : the official publication of the Association for Academic Minority Physicians·2002
Same journal

Early detection and screening for ovarian cancer: does physician specialty matter?

Journal of the Association for Academic Minority Physicians : the official publication of the Association for Academic Minority Physicians·2002
See all related articles

Multidrug-resistant tuberculosis (MDR-TB) is a global health crisis. This review covers MDR-TB epidemiology, resistance mechanisms, and treatment strategies, including novel therapies.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Public Health

Background:

  • Multidrug-resistant tuberculosis (MDR-TB) poses a significant global health threat.
  • Mycobacterium tuberculosis infects approximately 2 billion people, causing millions of new cases and tens of thousands of deaths annually.
  • Drug resistance in tuberculosis can be acquired or develop during treatment due to non-compliance or inadequate regimens.

Purpose of the Study:

  • To review the epidemiology of tuberculosis and drug resistance.
  • To discuss the likelihood and molecular mechanisms of resistance development.
  • To present principles for preventing nosocomial transmission and treatment approaches for MDR-TB.

Main Methods:

  • Literature review of tuberculosis epidemiology and drug resistance.

Related Experiment Videos

  • Discussion of molecular mechanisms of drug resistance.
  • Analysis of prevention strategies, treatment options, and novel therapies for MDR-TB.

    • Main Results:

    • Drug resistance can be acquired or develop during treatment.
    • Molecular mechanisms underlying resistance to various drugs are elucidated.
    • Prevention of nosocomial transmission and effective treatment regimens are crucial.

    Conclusions:

    • MDR-TB requires comprehensive strategies for prevention and treatment.
    • Novel therapeutic approaches, including phenothiazines and suicide genes, show potential.
    • Addressing patient compliance and treatment adequacy is vital to combatting MDR-TB.