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Conditional Reprogramming of Pediatric Human Esophageal Epithelial Cells for Use in Tissue Engineering and Disease Investigation
10:15

Conditional Reprogramming of Pediatric Human Esophageal Epithelial Cells for Use in Tissue Engineering and Disease Investigation

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[Parents of children with esophageal atresia--important source of knowledge]

Anne Faugli1, Kristin Bjørnland, Hans Skari

  • 1Barne- og ungdomspsykiatrisk seksjon Barneklinikken, Rikshospitalet 0027 Oslo. anne.faugli@klinmed.uio.no

Tidsskrift for Den Norske Laegeforening : Tidsskrift for Praktisk Medicin, Ny Raekke
|October 5, 2002
PubMed

Insights

Parents report that children with oesophageal atresia (OA) experience ongoing respiratory, feeding, and psychosocial issues well beyond early childhood. These findings highlight the need for long-term, comprehensive care for OA patients.

Area of Science:

  • Pediatric Surgery
  • Developmental Pediatrics
  • Child Psychology

Context:

  • Oesophageal atresia (OA) is a congenital condition often associated with early childhood feeding and respiratory difficulties.
  • Long-term psychosocial outcomes and parental perspectives on OA are less understood.
  • Comprehensive biopsychosocial follow-up is crucial for managing OA patients.

Purpose:

  • To investigate the long-term somatic and psychosocial functioning of children and adolescents with oesophageal atresia from a parental perspective.
  • To assess parental satisfaction with health services provided to children with OA.
  • To inform the design of a comprehensive biopsychosocial follow-up study.

Summary:

  • Parents of 25 children (median age 4 years) with OA completed a questionnaire on their child's health.
  • Key reported issues included recurrent respiratory infections, chronic cough, wheezing, and significant swallowing difficulties.
  • Psychosocial challenges, particularly around mealtimes, were also frequently noted by parents.

Impact:

  • Parental reports indicate that respiratory, feeding, and psychosocial problems associated with oesophageal atresia persist into later childhood and adolescence.
  • Findings underscore the necessity for continued, multidisciplinary support beyond the neonatal period.
  • This study provides valuable insights for developing targeted interventions and improving long-term care strategies for individuals with OA.
Abstract

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