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[Is antibiotic prophylaxis in Cesarean section necessary?].

Ingrid Petrikke Olsen1, Kåre Augensen, Arnold Jensen

  • 1Hammerfest sykehus 9600 Hammerfest. ingrid.petrikke.olsen@hammerfest-sykehus.no

Tidsskrift for Den Norske Laegeforening : Tidsskrift for Praktisk Medicin, Ny Raekke
|October 5, 2002
PubMed
Summary

Selective prophylactic antibiotics for caesarean sections were evaluated. The study found no significant difference in infection rates between groups receiving and not receiving antibiotics, questioning routine prophylaxis recommendations.

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Area of Science:

  • Obstetrics and Gynecology
  • Infectious Disease Prevention

Background:

  • Cochrane Review recommends routine prophylactic antibiotics for all caesarean sections to reduce endometritis.
  • This study assesses infection rates with selective antibiotic prophylaxis in a single hospital.

Purpose of the Study:

  • To evaluate the infection rate after caesarean section in a hospital using selective prophylactic antibiotic administration.
  • To compare infection rates between women receiving and not receiving prophylactic antibiotics.

Main Methods:

  • Retrospective study of 344 caesarean section case records.
  • Postoperative wound infection assessed via questionnaire at 30 days in 83% of patients.

Main Results:

  • 39% of patients received prophylactic antibiotics.

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  • 9.6% developed post-cesarean infections; no significant difference between elective/non-elective or antibiotic/no antibiotic groups (p=0.63, p=0.84).
  • Only one patient had endometritis.

    • Conclusions:

    • Selective prophylactic antibiotic use for caesarean sections was successful in this hospital.
    • Results question the universal recommendation for routine prophylactic antibiotics from the Cochrane Review.
    • Further research is needed to determine if selective prophylaxis is superior to routine prophylaxis.