Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Atopic dermatitis and fungi.

Jan Faergemann¹

¹Department of Dermatology, Sahlgrenska University Hospital, Gothenburg, Sweden. jan.faergemann@derm.gu.se

Clinical Microbiology Reviews

|October 5, 2002

Summary

Atopic dermatitis (AD) is a chronic inflammatory skin condition. Investigating microorganisms like Malassezia and Candida, and dermatophytes, may reveal new treatment avenues for patients unresponsive to standard therapies.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Skin Health Connected to the Use of Absorbent Hygiene Products: A Review.

Dermatology and therapy·2017

Same author

Variation in Staphylococcus aureus Colonization in Relation to Disease Severity in Adults with Atopic Dermatitis during a Five-month Follow-up.

Acta dermato-venereologica·2017

Same author

A retrospective analysis of skin bacterial colonisation, susceptibility and resistance in atopic dermatitis and impetigo patients.

Acta dermato-venereologica·2014

Same author

Bacteria aerosol spread and wound bacteria reduction with different methods for wound debridement in an animal model.

Acta dermato-venereologica·2014

Same author

The effect of K101 Nail Solution on Trichophyton rubrum and Candida albicans growth and ultrastructure.

Mycoses·2014

Same author

Comparison of dermatophyte PCR kit with conventional methods for detection of dermatophytes in skin specimens.

Mycopathologia·2013

Area of Science:

Dermatology
Immunology
Microbiology

Background:

Atopic dermatitis (AD) is a chronic, itchy, inflammatory skin disease often linked to asthma and hay fever, with genetic factors playing a role.
Impaired skin barrier function in AD patients increases sensitivity to irritants and microorganisms.
Standard treatments include topical corticosteroids, immunomodulators, emollients, and phototherapy, but some patients show limited response.

Purpose of the Study:

To explore the role of microorganisms, specifically yeasts like Malassezia and Candida, and dermatophytes in atopic dermatitis.
To investigate potential therapeutic strategies targeting microbial factors in AD management.

Main Methods:

Review of existing literature on the role of Malassezia yeasts, Candida species, and dermatophytes in atopic dermatitis.
Analysis of studies documenting the impact of these microorganisms on AD, particularly in cases resistant to conventional treatments.

Main Results:

Growing evidence supports the involvement of Malassezia yeasts in AD, especially in head and neck regions.
Candida species are indicated as potential aggravating factors in AD.
Patients with AD are more susceptible to chronic dermatophyte infections, and antifungal treatment may improve AD symptoms.

Conclusions:

Microbial factors, including Malassezia, Candida, and dermatophytes, represent an important consideration in managing atopic dermatitis, particularly in treatment-resistant cases.
Antifungal therapies may offer a beneficial treatment option for AD patients with co-existing fungal infections.

Related Experiment Videos