Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Parietal representation of object-based saccades.

Philip N Sabes1, Boris Breznen, Richard A Andersen

  • 1Division of Biology, California Institute of Technology, Pasadena, California 91125, USA.

Journal of Neurophysiology
|October 5, 2002
PubMed
Summary

Neurons in the lateral intraparietal area (LIP) maintain eye-centered (retinotopic) coding for saccadic eye movements, even when targets are part of a moving object. This suggests LIP uses consistent spatial representations for directing gaze.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Duration-modulated neural population dynamics in humans during BMI controls.

Communications biology·2026
Same author

The Compositional Encoding of Hand-Eye Coordinated Movements for Single Neurons in the Posterior Parietal Cortex.

bioRxiv : the preprint server for biology·2026
Same author

Real-time brain-computer interface control of walking exoskeleton with bilateral sensory feedback.

Brain stimulation·2026
Same author

Hierarchical and Context-Dependent Encoding of Actions in Human Posterior Parietal and Motor Cortex.

bioRxiv : the preprint server for biology·2025
Same author

Charge density of multi-channel intra-cortical micro-stimulation modulates intensity and naturalness of evoked somatosensations.

Journal of neural engineering·2025
Same author

Visual context affects the perceived timing of tactile sensations elicited through intracortical microstimulation: a case study of two participants.

Journal of neurophysiology·2025

Area of Science:

  • Neuroscience
  • Cognitive Neuroscience
  • Primate Vision

Background:

  • Neurons in the lateral intraparietal area (LIP) typically encode saccadic eye movement targets using a retinotopic (eye-centered) frame of reference.
  • Natural behaviors often involve saccadic eye movements directed towards objects, not just simple visual targets.
  • The neural representation of saccade targets on objects versus absolute spatial locations remains an open question.

Purpose of the Study:

  • To investigate whether the lateral intraparietal area (LIP) represents saccadic eye movements differently when targets are specified as part of a visually displayed object.
  • To determine if LIP neurons exhibit object-fixed representations or maintain retinotopic coding when targeting objects in motion.

Main Methods:

  • Monkeys performed an object-based saccade task requiring saccades to cued object parts after object reappearance in a new orientation.

Related Experiment Videos

  • Single-neuron recordings were conducted in LIP during the object-based saccade task and control tasks (memory saccade, fixation).
  • Hierarchical generalized linear models analyzed firing rates based on retinotopic location, object-fixed location, and object orientation.

    • Main Results:

    • A majority of LIP neurons tuned in a standard memory saccade task were also tuned in the object-based saccade task.
    • No evidence of explicit object-fixed representations was found; no neurons showed receptive fields rotating with the object.
    • Firing rates were primarily explained by retinotopic target direction and object orientation, with retinotopic effects dominating near motor response.

    Conclusions:

    • The lateral intraparietal area (LIP) consistently uses retinotopic coding for saccade targets, regardless of whether the target is a fixed spatial point or a location on a moving object.
    • Object orientation influences LIP activity, but this effect is interpreted as modulating the retinotopic coding of potential target locations on the object.
    • LIP's spatial representation for saccadic eye movements remains primarily eye-centered, even during complex object-based tasks.