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[Treatment decision as a function of cardiovascular risk in isolated systolic hypertension in general medicine. The
T Denolle1, H Gallois, P L'Hostis
1Unité HTA, centre de prévention cardiovasculaire, hôpital La Providence Gardiner, 35800 Dinard.
Insights
General practitioners consider patient risk factors when deciding on isolated systolic hypertension (ISH) treatment. While most decisions align with guidelines, some patients with low or high cardiovascular risk were undertreated or overtreated.
Area of Science:
- Cardiology
- General Practice
- Public Health
Context:
- Isolated systolic hypertension (ISH) affects a significant patient population.
- General practitioners (GPs) manage ISH, influencing cardiovascular disease (CVD) risk.
- Understanding treatment decisions in ISH is crucial for effective hypertension management.
Purpose:
- To analyze the treatment decisions made by GPs for patients with isolated systolic hypertension (ISH).
- To identify patient characteristics influencing GP treatment choices in ISH.
- To evaluate adherence to ISH treatment recommendations.
Summary:
- A study of 11,436 patients with ISH (SBP ≥ 140, DBP < 90 mmHg) examined GP treatment decisions.
- GPs considered ISH grade, risk factors, and cardiovascular risk levels, aligning with recommendations in 91% of cases.
- However, discrepancies were noted, with undertreatment in low-risk and overtreatment in high-risk patients.
Impact:
- Findings highlight the importance of considering multiple factors in ISH treatment decisions.
- Reveals potential gaps in adhering to ISH guidelines, particularly for low and high-risk individuals.
- Informs strategies for optimizing hypertension management and reducing cardiovascular events.
Objective:
To analyse the decision of treatment made by the GP, based on the characteristics of patients with isolated systolic hypertension (ISH).
Methods:
11,436 patients with SBP > or = 140 and DBP < 90 mmHg were examined by 1,464 GPs who filled out a questionnaire for each patient, which included the patient's BP, risk factors, the presence of target organ damage (TOD), antihypertensive treatment and the physician's decision of treatment during the visit. Before the visit, 4,378 patients were not treated: 57 +/- 13 years: 53% men: BP: 157/81 mmHg; smokers: 30%; diabetes: 8%; dyslipidemia: 17%; BMI > 25 kg/m2: 54%; TOD: 11%. Thus, according to ISH tables, 15% of the patients who were not treated presented a low cardiovascular risk (LR), 69% a medium risk (MR), and 16% a high risk (HR). After the visit, 2,599 patients (59%) started antihypertensive treatment. [table: see text]
Conclusion:
78% of the patients with ISH had at least one other risk factor. Three elements (the grade of ISH, the number of risk factors and the level of CV risks) are significantly taken into account in making the decision of treatment. Decision of treatment was in accordance with ISH recommendation in 91% of patients. Nevertheless, while ISH recommendations are life style measures, only when a LR exists, 39% with a LR were treated. On the other hand, 24% with a HR were not treated.
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Hypertension I: Introduction
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Hypertension III: Clinical Manifestations and Diagnostic Studies
Hypertension IV: Drug Therapy and Lifestyle Modifications
Atherosclerosis III: Management

