Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Future therapies.

Clifford J Bailey1, Caroline Day

  • 1School of Pharmacy, Aston University, Birmingham, UK. c.j.bailey@aston.ac.uk

Current Medical Research and Opinion
|October 9, 2002
PubMed
Summary
This summary is machine-generated.

New diabetes therapies aim to restore normal glucose levels by improving insulin action and release. Emerging treatments include novel agents and gene therapy for type 1 and type 2 diabetes.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cardiorenal effects of therapies for type 2 diabetes and obesity.

The British journal of cardiology·2026
Same author

Metformin: Antidiabetic actions from cells to tissues.

Metabolism: clinical and experimental·2026
Same author

Long-acting amylin-related peptides as therapies for obesity and type 2 diabetes.

Peptides·2026
Same author

Pharmacological therapies for type 2 diabetes: future approaches.

Diabetologia·2025
Same author

Multifunctional incretin peptides in therapies for type 2 diabetes, obesity and associated co-morbidities.

Peptides·2025
Same author

Diabetes and gout: another role for SGLT2 inhibitors?

Therapeutic advances in endocrinology and metabolism·2024
Same journal

Multidrug-resistant <i>Pseudomonas aeruginosa</i> in Jordan: epidemiology, trends, determinants, and clinical outcomes.

Current medical research and opinion·2026
Same journal

RSV disease and vaccination knowledge, attitudes, and practices among US adults: a 2024-2025 RSV season survey.

Current medical research and opinion·2026
Same journal

Clinical and healthcare resource utilization outcomes following revision knee arthroplasty with and without a gradually reducing radius revision knee system.

Current medical research and opinion·2026
Same journal

Medication adherence measurement methods and their reported relationship with medication safety outcomes: a scoping review.

Current medical research and opinion·2026
Same journal

BMI response to dapagliflozin with or without semaglutide across obesity classes: a real-world observational study conducted in Saudi Arabia.

Current medical research and opinion·2026
Same journal

Comparative efficacy of tislelizumab + FOLFOX or CAPOX for gastric/gastroesophageal junction adenocarcinoma: an exploratory matching-adjusted indirect comparison.

Current medical research and opinion·2026
See all related articles

Area of Science:

  • Endocrinology
  • Pharmacology
  • Metabolic Diseases

Background:

  • Type 1 and type 2 diabetes require improved therapies to achieve near-normal glucose homeostasis.
  • Current intensive therapy use shows benefits, with new agents under development.

Purpose of the Study:

  • To review emerging and novel therapeutic strategies for managing type 1 and type 2 diabetes.
  • To explore advancements in agents that mimic insulin action, enhance insulin secretion, and promote beta-cell health.

Main Methods:

  • Review of current literature on diabetes therapies.
  • Analysis of novel agents targeting insulin signaling, insulin release, and beta-cell function.
  • Consideration of gene therapy as a future treatment option.

Related Experiment Videos

Main Results:

  • Agents improving insulin action (e.g., PPARgamma agonists) and insulin signaling are progressing.
  • Novel therapies enhancing nutrient-stimulated insulin release and beta-cell replication/neogenesis are emerging.
  • Obesity and dyslipidemia management are key components of new therapeutic approaches.
  • Gene therapy presents a potential future strategy for beta-cell replacement.

Conclusions:

  • Significant advancements are being made in developing new therapies for diabetes.
  • A multi-faceted approach involving improved insulin action, enhanced secretion, beta-cell regeneration, and metabolic control is crucial.
  • Future therapeutic options for diabetes are diverse, including pharmacological and genetic interventions.