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Treatment of chronic ischaemia of a replanted thumb with iloprost

M Sabovic1

  • 1Department for Vascular Diseases, Internal Clinic, University Medical Centre, Ljubljana, Slovenia. miso.sabovic@trnovo.kclj.si

Journal of Hand Surgery (Edinburgh, Scotland)
|October 9, 2002
PubMed

Insights

Iloprost treatment improved chronic ischemia in a replanted thumb by enhancing microcirculation flow, even with occluded digital arteries. This suggests a potential therapeutic benefit for similar cases.

Area of Science:

  • Vascular Surgery
  • Reconstructive Surgery
  • Pharmacology

Background:

  • Chronic ischemia can compromise the viability of replanted digits.
  • Digital artery occlusion and poor collateral circulation present significant challenges in managing replant ischemia.

Observation:

  • A 40-year-old male patient presented with chronic ischemia of a replanted thumb.
  • Angiography demonstrated occlusion of both digital arteries and inadequate collateral vessels.

Findings:

  • The patient received a 4-week course of Iloprost therapy.
  • Iloprost administration resulted in definite and sustained clinical improvement.
  • Improvement persisted despite the continued occlusion of the digital arteries.

Implications:

  • Iloprost may enhance microcirculation and collateral flow, offering a therapeutic option for digital ischemia.
  • This finding suggests a potential non-invasive treatment strategy for chronic ischemia in replanted extremities.
  • Further research into Iloprost's mechanism in improving microvascular perfusion is warranted.

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