Related Experiment Videos
Determination of CMC of sodium glucocorticides hemisuccinates by CE
Yahya Mrestani1, Sven Claussen, Reinhard H H Neubert
1Institute of Pharmaceutics and Biopharmaceutics, Martin-Luther-University, Halle-Wittenberg, Wolfgang-Langenbeck-Strasse 4, 06120 Halle/S, Germany. mrestani@pharmazie.uni-halle.de
Journal of Pharmaceutical and Biomedical Analysis
|October 9, 2002
Abstract:
The capillary zone electrophoresis (CZE) method was applied to the determination of the critical micelle concentration (CMC) and the anionic mobilities (mu(e)) for sodium glycocorticides hemisuccinates (Urbason solubile forte 1000, Hydrocortison 100 Rotexmedica, Prednisolut 100) in phosphate solution at pH 7.2. The CZE enables an efficient and very fast determination of parameters for characterizing physicochemical properties of micelles.