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Updated: Sep 29, 2026

Using Fluorescence In Situ Hybridization (FISH) to Monitor the State of Arm Cohesion in Prometaphase and Metaphase I Drosophila Oocytes
Published on: December 6, 2017
Chromosome cohesion: ring around the sisters?
Joseph L Campbell1, Orna Cohen-Fix
1The Laboratory of Molecular and Cellular Biology, NIDDK, NIH 8 Center Drive, Bethesda, MD 20892, USA.
Abstract:
Sister chromatid cohesion is a key aspect of accurate chromosome transmission during mitosis, yet little is known about the structure of cohesin, the protein complex that links the two sister chromatids. Recent studies shed light on the structure of the cohesin complex, leading to intriguing models that could explain how sister chromatids are held together.
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