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Nontuberculous mycobacterial infections in pediatric acute leukemia
Kaveri Suryanarayan1, James Campbell, Allen E Eskenazi
1Department of Pediatrics and the Marlene and Stuart Greenebaum Cancer Center, University of Maryland School of Medicine, Baltimore 21201, USA. ksuryanarayan@peds.umaryland.edu
Abstract:
We report on 3 children undergoing treatment for acute lymphoblastic leukemia (ALL), who developed systemic nontuberculous mycobacterial (NTM) infections. All 3 patients were treated successfully with 5 months or less of antimicrobial therapy and completed their chemotherapy with no further recurrence of their NTM infection. NTM infections in some children with ALL may be successfully treated with antimicrobial agents without necessarily compromising the ALL treatment. The optimal duration of therapy for NTM remains unclear, but may be shorter than previously reported.