Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Evidence for left ventricular constraint during open heart surgery.

Israel Belenkie1, Teresa M Kieser, Rozsa Sas

  • 1Department of Medicine, University of Calgary, Canada. Belenkie@ucalgary.ca

The Canadian Journal of Cardiology
|October 9, 2002
PubMed
Summary

Cardiac surgery constrains heart filling due to thoracic structures. Pulmonary capillary wedge pressure (PCWP) is unreliable for assessing left ventricular (LV) filling during these procedures.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Impact of cannabidiol on myocardial recovery in patients with acute myocarditis: primary results of the ARCHER study.

ESC heart failure·2026
Same author

Life & Advice from the Giants in Cardiac Surgery: Giving & Receiving; Leading & Following.

Brazilian journal of cardiovascular surgery·2024
Same author

Impact of cannabidiol on myocardial recovery in patients with acute myocarditis: Rationale & design of the ARCHER trial.

ESC heart failure·2024
Same author

Cardiac surgery elicits pericardial inflammatory responses that are distinct compared with postcardiopulmonary bypass systemic inflammation.

JTCVS open·2024
Same author

Comprehensive characterization of the postoperative pericardial inflammatory response: Potential implications for clinical outcomes.

JTCVS open·2023
Same author

Graft flow evaluation with intraoperative transit-time flow measurement in off-pump versus on-pump coronary artery bypass grafting.

JTCVS techniques·2022

Area of Science:

  • Cardiovascular Physiology
  • Thoracic Surgery
  • Echocardiography

Background:

  • The extent to which thoracic structures limit cardiac function during surgery is not well understood.
  • Accurate assessment of cardiac filling is crucial for patient management.

Purpose of the Study:

  • To quantify the constraint on left ventricular (LV) filling during cardiac surgery.
  • To evaluate the reliability of pulmonary capillary wedge pressure (PCWP) as a measure of LV preload in this setting.

Main Methods:

  • Measured central venous pressure (CVP), PCWP, and LV end-diastolic volume (LVEDV) via transesophageal echocardiography in 12 patients.
  • Assessed LV filling pressures and volumes at various surgical stages.
  • Plotted PCWP and transmural LV end-diastolic pressure (LVEDP) against LV area.

Related Experiment Videos

Main Results:

  • Significant constraint to LV filling was observed in all patients.
  • PCWP consistently overestimated LV filling pressure, even when transmural LVEDP was near zero.
  • LV area-transmural LVEDP relationships were deemed more accurate than PCWP-LV area relationships.

Conclusions:

  • The lungs and mediastinal structures impose considerable constraint on cardiac filling during surgery.
  • PCWP is an unreliable indicator of LV preload in the context of cardiac surgery.
  • Clinicians must consider this constraint when interpreting LV filling pressures.