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Inhibitory mechanisms of antibiotics targeting elongation factor Tu

T Hogg1, J R Mesters, R Hilgenfeld

  • 1Department of Structural Biology and Crystallography, Institute of Molecular Biotechnology, Beutenbergstrasse 11, D-07745 Jena, Germany.

Current Protein & Peptide Science
|October 9, 2002
PubMed
Summary

Bacterial elongation factor Tu (EF-Tu) is a promising antimicrobial target. Recent structural studies of EF-Tu inhibitors like aurodox and GE2270A provide a foundation for developing new antibiotics.

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