Related Experiment Videos
Crystallization and preliminary X-ray diffraction analysis of FKBP12 complexed with a novel neurotrophic ligand
Pengyun Li1, Liwei Wang, Yi Ding
1Laboratory of Structural Biology, Department of Biological Science and Technology & MOE Laboratory of Protein Science, Tsinghua University, Beijing 100084, China.
Protein and Peptide Letters
|October 9, 2002
Abstract:
A novel neurotrophic ligand, (3R)-4-(p-Toluenesulfonyl)-1,4-thiazane-3-carboxylic acid-L-Leucine ethyl ester, has been complexed with FKBP12 and crystallized using the hanging-drop vapor-diffusion method. Crystals belong to P2(1) space group, with unit cell parameters a=41.2, b=29.6, c=41.5 A, beta=114.0 degrees. The crystals diffract to 1.8 A resolution limit.