Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Urticaria to cetirizine.

R Tella1, P Gaig, J Bartra

  • 1Allergy Unit, Hospital Universitari Joan XXIII, Tarragona, Spain.

Journal of Investigational Allergology & Clinical Immunology
|October 10, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Comments to Reply to "Differences in Molecular Sensitization Profiles Between Spanish and Latin American Mite-Allergic Patients".

Journal of investigational allergology & clinical immunology·2025
Same author

Basal Serum Tryptase Outperforms Hereditary Alpha Tryptasemia as a Biomarker of Food Allergy Severity.

Allergy·2025
Same author

Gastrointestinal Symptoms: Under the Tip of the Iceberg in Lipid Transfer Protein Food Allergy.

Journal of investigational allergology & clinical immunology·2024
Same author

Mast Cell Activation Profile and TFH13 Detection Discriminate Between Food Anaphylaxis and Sensitization.

Journal of investigational allergology & clinical immunology·2024
Same author

Biomarkers predicting the controller dose of omalizumab in patients with chronic spontaneous urticaria.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology·2024
Same author

Low levels of miR-143-3p are associated with severe chronic rhinosinusitis with nasal polyps.

Rhinology·2024
Same journal

Effect of Dupilumab on Sleep Disturbance in Patients With Uncontrolled Moderate-to-Severe Asthma, Type 2 Inflammation, and Nocturnal Awakenings: The MORPHEO Randomized Controlled Trial.

Journal of investigational allergology & clinical immunology·2026
Same journal

Severe Rituximab-Induced Cytokine Release Syndrome After Desensitization Successfully Treated With Tocilizumab: A Case Report.

Journal of investigational allergology & clinical immunology·2026
Same journal

Dysregulation of Mast Cell Prostaglandin in Food Anaphylaxis.

Journal of investigational allergology & clinical immunology·2026
Same journal

Extract-Negative Cofactor-Dependent Shrimp Anaphylaxis Caused by IgE Reactivity to Insoluble Muscle Proteins.

Journal of investigational allergology & clinical immunology·2026
Same journal

Antibiotic Allergy Labels in Hospitalized Patients: Results of a Multicenter Cross-Sectional Study.

Journal of investigational allergology & clinical immunology·2026
Same journal

Grass Pollen Exposure in an Environmental Exposure Chamber vs Natural Exposure: A Clinical Comparison of Symptoms.

Journal of investigational allergology & clinical immunology·2026
See all related articles

A patient experienced worsening urticaria with cetirizine, despite negative skin tests. Challenge tests confirmed hydroxyzine and cetirizine triggered the condition, highlighting rare antihistamine adverse reactions.

Area of Science:

  • Allergy and Immunology
  • Pharmacology

Background:

  • Idiopathic urticaria is a common condition often treated with H1 antihistamines.
  • Adverse reactions to antihistamines can complicate diagnosis and treatment.

Observation:

  • A patient with recurrent idiopathic urticaria reported symptom exacerbation following cetirizine treatment.
  • Standard allergy testing, including prick tests for cetirizine, yielded negative results.

Findings:

  • Double-blind placebo-controlled challenge tests demonstrated that hydroxyzine and its active metabolite, cetirizine, reproduced the patient's urticaria.
  • Other H1 antihistamines (mizolastine, loratadine, fexofenadine, dexchlorpheniramine, ebastine, ketotifen) did not trigger reactions.

Implications:

Related Experiment Videos

  • This case highlights the importance of considering uncommon adverse drug reactions to H1 antihistamines.
  • Such reactions can mimic or exacerbate the symptoms of the underlying condition, complicating clinical management.