Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The first international consensus conference on continuous renal replacement therapy.

John A Kellum1, Ravindra L Mehta, Derek C Angus

  • 1Department of Critical Care Medicine and Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA. kellumja@anes.upmc.edu

Kidney International
|October 10, 2002
PubMed
Summary

Critical care guidelines for acute renal failure (ARF) are lacking. This review established some consensus on continuous renal replacement therapy (CRRT) but highlights the need for more research.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Hepatorenal syndrome treated for eight months with continuous-flow peritoneal dialysis.

Advances in peritoneal dialysis. Conference on Peritoneal Dialysis·2013
Same author

Year in review 2012: Critical Care--Nephrology.

Critical care (London, England)·2013
Same author

Healthcare systems and chronic kidney disease: putting the patient in control.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association·2013
Same author

Neutrophil gelatinase associated lipocalin in acute kidney injury.

Postgraduate medicine·2013
Same author

Ultrafiltration therapy for acute decompensated heart failure: lessons learned from 2 major trials.

American heart journal·2013
Same author

Potential use of biomarkers in acute kidney injury: report and summary of recommendations from the 10th Acute Dialysis Quality Initiative consensus conference.

Kidney international·2013

Area of Science:

  • Nephrology
  • Critical Care Medicine
  • Evidence-Based Medicine

Background:

  • Management of acute renal failure (ARF) in critically ill patients lacks standardized protocols for renal replacement therapy.
  • Significant variability exists in current clinical practice.
  • This study aimed to review evidence, establish practice recommendations, and identify research gaps.

Framework:

  • An evidence-based review of continuous renal replacement therapy (CRRT) literature was conducted using MEDLINE.
  • A consensus conference convened experts to develop summary statements and practice guidelines.
  • Key questions regarding CRRT in ARF were addressed.

Implementation:

  • Consensus was reached on 20 out of 46 key questions regarding CRRT.
  • Inadequate evidence precluded consensus on 21 questions.

Related Experiment Videos

  • Data existed for 5 questions, but no consensus was achieved.

    • Implications:

    • Broad consensus exists for the use of CRRT in ARF, supporting guideline development.
    • Significant areas of disagreement highlight the need for further research.
    • Additional basic and applied research is crucial for advancing ARF management.