Related Experiment Video
Updated: Aug 9, 2026

Using the Threat Probability Task to Assess Anxiety and Fear During Uncertain and Certain Threat
Published on: September 12, 2014
[Paroxetine treatment for children and adolescents with anxiety disorders]
H Blasco-Fontecilla1, A Madoz-Gúrpide, J San Sebastián Cabasés
1Unidad de Psiquiatría Infantil, Servicio de Psiquiatría, Hospital Ramón y Cajal, Universidad de Alcalá, Madrid, Spain. hmblasco@yahoo.es
Background:
Paroxetine has become an effectiveness treatment in anxiety disorders in adults. Despite the fact that this is an especially prevalent psychiatrist disorder in children and adolescents, there are very few studies in this population. This study examines the effectiveness of paroxetine in children and adolescents with anxiety disorders.
Methodology:
Fifteen children and adolescents with ICD-criteria for anxiety disorder were selected. Anxiety measurement was taken with STAI scale and was filled out before treatment and 6 months later (mean). We have used descriptive parameters and t Student test for the analysis of dependent samples. Statistic work was done with SPSS 8.0.
Results:
On first testing, the mean score for State Factor was 41.8 (ds: 5.9) and on second after treatment- it was 24.66 (ds: 9.8). Trait Factor was 43.53 (ds: 8.27) on first testing and 25 (ds: 8.91) on second. These differences in mean scores for both State and Trait factors were significant (alpha=0.05, p= 0.000).
Conclusions:
Our results support the hypothesis of clinical improvement at Anxiety Disorders in children and adolescent using Paroxetine. It seems logical to continue the study increasing sample size and evaluation time.
Related Concept Videos
Antidepressant Drugs: Tricyclics, SSRIs, and SNRIs
Antidepressant Drugs: MAOIs and Other Agents
Anxiolytic Drugs: Overview
Primary Types of Anxiolytic Drugs
1. Benzodiazepines:
Benzodiazepines bind to the GABA-A receptor in the brain, enhancing GABA's interaction. This action reduces neurotransmission, effectively blocking anxiety-associated limbic circuitry.
Anxiolytic Drugs: Benzodiazepines and Buspirone
Panic Disorder
Behavior Therapy
Exposure therapy is a cornerstone of behavioral treatment for anxiety disorders. It involves systematic exposure to feared stimuli, either in real...

