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Bacteremic and leukopenic pneumococcal pneumonia: successful treatment with antibiotics, pulse steroid, and
Toshinobu Yokoyama1, Teruo Sakamoto, Norihiko Shida
1First Department of Internal Medicine, Kurume University School of Medicine, Fukuoka, Japan. yokoyama-t@nyc.odn.ne.jp
Abstract:
We describe a case of bacteremic, leukopenic pneumococcal pneumonia with respiratory failure, accompanied by diabetic ketoacidosis and hypothermia. Pulmonary leukostasis may play a role in the pathogenesis of the acute respiratory distress syndrome (ARDS) in pneumococcal pneumonia. The patient recovered with mechanical ventilation, intravenous antibiotics, pulse-steroid therapy, and continuous hemodiafiltration (CHDF). In particular, administration of steroid and the use of CHDF may improve the status of pulmonary leukostasis in leukopenic pneumococcal infection.