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Mimicking gangliosides by design: mimics of GM1 headgroup
Anna Bernardi1, Daniela Arosio, Sandro Sonnino
1Universita' di Milano, Dipartimento di Chimica Organica e Industriale, Italy. Anna.Bernardi@unimi.it
Neurochemical Research
|October 11, 2002
Abstract:
Detailed knowledge of the three-dimensional structure of ganglioside headgroups has allowed the successful design of structural and functional mimics of ganglioside GMI oligosaccharide. Our recent work in this area is reviewed in this paper.