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Intramolecular Baylis-Hillman and morita reactions using unsaturated thiol ester substrates containing enolizable
1Department of Chemistry, University of Utah, Salt Lake City, Utah 84112-0850, USA. keck@chemistry.utah.edu
Organic Letters
|October 12, 2002
Abstract:
[reaction: see text] Previously unknown intramolecular Baylis-Hillman and Morita reactions involving cyclization of an unsaturated thiol ester onto a pendant aldehyde function are reported. These can be used successfully for the preparation of both cyclopentenols and cyclohexenols, but the results are very sensitive to substrate and precise reaction conditions.