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Updated: Aug 15, 2026

Reduction in Left Ventricular Wall Stress and Improvement in Function in Failing Hearts using Algisyl-LVR
Published on: April 8, 2013
Volume reduction surgery for end-stage ischemic heart disease
Takahiro Shiota1, Patrick M McCarthy
1Department of Cardiology, The Cleveland Clinic Foundation, Cleveland, Ohio, 44195, USA. shiota@cluba.com
Insights
The Dor procedure significantly improves ejection fraction in patients with ischemic heart failure. This surgery offers a high survival rate, confirming its value for advanced heart conditions.
Area of Science:
- Cardiology
- Cardiac Surgery
- Medical Imaging
Background:
- End-stage ischemic heart failure presents a significant clinical challenge.
- The Dor procedure (infarction excision surgery) is a surgical option for these patients.
- Echocardiography is crucial for assessing cardiac function and surgical outcomes.
Purpose of the Study:
- To evaluate the efficacy and outcomes of the Dor procedure for end-stage ischemic heart failure.
- To highlight the role of echocardiography in assessing surgical results.
- To emphasize the importance of surgeon-echocardiographer collaboration.
Main Methods:
- Analysis of a multicenter study involving 439 patients undergoing the Dor procedure.
- Utilizing echocardiography, including intraoperative transesophageal echocardiography, for cardiac assessment.
- Reviewing preoperative mortality and 18-month survival rates.
Main Results:
- Average ejection fraction increased from 29% to 39% post-surgery.
- Overall 18-month survival rate was 89%.
- Preoperative mortality rate was 6.6%.
Conclusions:
- The Dor procedure is a valuable surgical treatment for end-stage ischemic heart failure.
- Echocardiography, particularly 3D echocardiography, is essential for evaluating surgical success.
- Effective communication between cardiac surgeons and echocardiographers is vital for optimal patient outcomes.
Abstract:
The Dor procedure, or infarction excision surgery, was first used in 1984. It is a surgical treatment option for patients with end-stage ischemic heart failure. In a recently published multicenter study that included a total of 439 patients, average ejection fraction increased from 29 +/- 10% to 39 +/- 12% after surgery. In our experience, the overall survival rate 18 months after surgery is 89%, and the preoperative mortality rate is 6.6%. These results are similar to the previous reports from Dor's group, which confirmed the certain value of the surgery. Echocardiography, including intraoperative transesophageal echocardiography, plays an important role in clarifying cardiac anatomies, absolute left ventricular (LV) volumes, ejection fraction, and mitral regurgitation in patients with ischemic heart failure undergoing this surgery. With the development of ultrasound and computer technology, three-dimensional echocardiography may be preferred when evaluating the surgical results, including determination of absolute LV volumes. Communication between experienced cardiac surgeons and echocardiographers in the operating room is essential for successful outcomes and reliable evaluation of the surgery.
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