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Trisomy 18 in a 20-year-old woman

Michael Kelly1, Bradley W Robinson, John W Moore

  • 1MCP Hahnemann School of Medicine, Philadelphia, Pennsylvania, USA.

Insights

This case study describes a 20-year-old female with trisomy 18, a condition rarely surviving infancy. It reviews management strategies for prolonged survival in individuals with this genetic disorder.

Area of Science:

  • Genetics
  • Pediatrics
  • Internal Medicine

Background:

  • Trisomy 18 (Edwards syndrome) is a severe genetic disorder.
  • Infantile mortality is high, with few individuals surviving past the first year.
  • Factors influencing long-term survival remain poorly understood.

Observation:

  • A case of a 20-year-old female with trisomy 18 is presented.
  • This individual achieved prolonged survival beyond typical expectations.
  • The case highlights the potential for extended lifespan in trisomy 18.

Findings:

  • Management strategies for older children and young adults with trisomy 18 are reviewed.
  • The case offers insights into the care required for extended survival.
  • Understanding contributing factors to longevity is crucial.

Implications:

  • This case expands the understanding of trisomy 18 survival.
  • It emphasizes the need for comprehensive, long-term care plans.
  • Further research into factors promoting prolonged survival is warranted.

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