Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Characterization of measles sequences from Pune, India.

Niteen Wairagkar1, Paul A Rota, Stephanie Liffick

  • 1National Institute of Virology, Pune, India.

Journal of Medical Virology
|October 12, 2002
PubMed
Summary

This study genetically characterized wild-type measles viruses in India. Six sequences were genotype D4, three were genotype D8, and two were genotype A, revealing genetic diversity.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Seroprevalence of Measles, Mumps, Rubella, and Varicella-Zoster Virus Antibodies-United States, 2017-March 2020.

The Journal of infectious diseases·2026
Same author

Measles Update - United States, January 1-April 17, 2025.

MMWR. Morbidity and mortality weekly report·2025
Same author

Immunogenicity and safety of a measles and rubella-containing vaccine at age 6 and 9 months in Bangladesh: an open-label, randomised trial.

The Lancet. Child & adolescent health·2025
Same author

The African Medicines Agency - A potential gamechanger that requires strategic focus.

PLOS global public health·2025
Same author

Continued elimination of measles, rubella and congenital rubella syndrome in the United States, January 2022-June 2024.

Vaccine·2025
Same author

The measles virus matrix F50S mutation from a lethal case of subacute sclerosing panencephalitis promotes receptor-independent neuronal spread.

Journal of virology·2024

Area of Science:

  • Virology
  • Genetics
  • Epidemiology

Background:

  • Measles remains a significant public health concern globally.
  • Understanding the genetic diversity of circulating measles virus strains is crucial for effective control strategies.

Purpose of the Study:

  • To perform the initial genetic characterization of wild-type measles viruses circulating in India.
  • To identify the genotypes of measles virus strains detected in Pune between 1996 and 1998.

Main Methods:

  • Detection of measles virus RNA using reverse transcription-polymerase chain reaction (RT-PCR) on throat swab samples.
  • Sequence analysis of the hemagglutinin (H) and nucleocapsid (N) genes of the detected measles virus strains.

Main Results:

Related Experiment Videos

  • Measles virus RNA was identified in 11 out of 14 throat swabs collected.
  • Sequence analysis revealed the presence of three distinct measles virus genotypes: D4 (six sequences), D8 (three sequences), and A (two sequences).

    • Conclusions:

    • The study identified genetic diversity among wild-type measles viruses circulating in India.
    • Ongoing virologic surveillance in India and neighboring regions is recommended to fully understand the genetic landscape of measles viruses.