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Updated: Sep 28, 2026

Three-dimensional Reconstruction of the Vascular Architecture of the Passive CLARITY-cleared Mouse Ovary
Published on: December 10, 2017
Observation of the ovary development and its blood vessels in 185 fetuses at different ages
1Department of Obstetrics and Gynecology, Guangzhou General Hospital of Guangzhou Command, Guangzhou 510010, China.
Objective:
To collect evidences for selecting the donors and optimal approaches for ovary transplantation.
Methods:
Fetal ovaries were sliced for microscopic examination and the number of primary oocytes and primordial follicles therein was observed. The volume of the ovaries and the external diameter of their vessels were measured and the origin of the vessels also observed.
Results:
Primary oocytes and primordial follicles were observed in almost equal abundance in the ovaries of the fetuses 21 weeks or older of age. The diameter of the vessels supplying the ovaries were less than 2 mm, and in 40.54% of the cases, both of the ovary vessels originated from the renal artery, with 35.14% from the aorta; in the 24.32% cases left, the vessels supplying the right ovaries started from the aorta and the other from the renal artery.
Conclusion:
The ovaries of the fetuses 21 weeks or older of age can be used as donors for transplantation, preferentially for implantation, but the vessels are too thin for uneventful anastomosis.
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