[Diagnostic difficulties in neuroendocrine carcinoma of the larynx]

The rare case of the large cell neuroendocrinic carcinoma of larynx was described. 66 years old man was treated by total laryngectomy because of melanoma. Postoperative, immunohistochemical study shoved large cell neuroendocrinic carcinoma. A special emphasis was put on the preoperative misdiagnose, limiting neck dissection. The authors point out, however, the difficulties of the pathologic differentiation caused by similarity of these tumors. The treatment and prognosis are discussed.