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Hirsuties.

R P R Dawber1

  • 1Oxford Hospitals, University of Oxford, United Kingdom. oxfordhairfound@aol.com

The Journal of Gender-Specific Medicine : JGSM : the Official Journal of the Partnership for Women'S Health at Columbia
|October 17, 2002
PubMed
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Hirsutism, or excess male-pattern hair growth in women, signals underlying health issues. Proper assessment is crucial to differentiate serious conditions from minor ones and manage potential long-term health risks.

Area of Science:

  • Endocrinology
  • Dermatology
  • Gynecology

Background:

  • Hirsutism is androgen-dependent hair growth in females, mimicking male patterns but with less severity.
  • Clinical diagnosis of hirsutism necessitates systematic evaluation for underlying pathologies.
  • Assessment must differentiate dangerous causes from trivial ones and evaluate short-term well-being and long-term health risks.

Purpose of the Study:

  • To systematically review the clinical implications and diagnostic considerations of hirsutism in females.
  • To outline the physiological mechanisms of androgenic activity relevant to hirsutism.
  • To identify common and significant causes of hirsutism.

Main Methods:

  • Review of physiological mechanisms of androgen production, transport, and action.

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  • Compilation of common etiological factors contributing to hirsutism.
  • Emphasis on differential diagnosis and risk stratification.

    • Main Results:

    • Androgenic activity involves three stages: production, transport (e.g., sex hormone-binding globulin), and intracellular action.
    • Identified causes include polycystic ovary syndrome, congenital adrenal hyperplasia, androgen-secreting tumors, Cushing's syndrome, hyperprolactinemia, and menopause.
    • Highlights the need for anthropologic and racial data in understanding female hair patterns.

    Conclusions:

    • Hirsutism requires thorough clinical assessment to identify underlying pathology and associated health risks.
    • Understanding the multi-stage physiological mechanisms of androgens is key to diagnosis.
    • Further research into racial and anthropologic variations in female hair patterns is needed.