Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Continuous renal replacement therapy: does technique influence azotemic control?

Hiroshi Morimatsu1, Shigehiko Uchino, Rinaldo Bellomo

  • 1Department of Intensive Care, Austin and Repatriation Medical Centre, Melbourne, Victoria.

Renal Failure
|October 17, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Hepatorenal syndrome treated for eight months with continuous-flow peritoneal dialysis.

Advances in peritoneal dialysis. Conference on Peritoneal Dialysis·2013
Same author

Year in review 2012: Critical Care--Nephrology.

Critical care (London, England)·2013
Same author

Healthcare systems and chronic kidney disease: putting the patient in control.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association·2013
Same author

Neutrophil gelatinase associated lipocalin in acute kidney injury.

Postgraduate medicine·2013
Same author

Ultrafiltration therapy for acute decompensated heart failure: lessons learned from 2 major trials.

American heart journal·2013
Same author

Potential use of biomarkers in acute kidney injury: report and summary of recommendations from the 10th Acute Dialysis Quality Initiative consensus conference.

Kidney international·2013

Continuous veno-venous hemofiltration (CVVH) demonstrated superior azotemic control compared to continuous veno-venous hemodiafiltration (CVVHDF) in critically ill acute renal failure patients. This study highlights technique-specific impacts on urea and creatinine levels during renal replacement therapy.

Area of Science:

  • Nephrology
  • Critical Care Medicine
  • Renal Replacement Therapy

Background:

  • Continuous renal replacement therapy (CRRT) encompasses various techniques with potentially differing impacts on azotemic control.
  • Understanding these differences is crucial for optimizing patient management in acute renal failure (ARF).

Purpose of the Study:

  • To compare the efficacy of continuous veno-venous hemodiafiltration (CVVHDF) and continuous veno-venous hemofiltration (CVVH) in controlling serum creatinine and plasma urea levels.
  • To determine if one CRRT technique offers superior azotemic control.

Main Methods:

  • A retrospective controlled study was conducted in two tertiary Intensive Care Units.
  • Data from critically ill patients with ARF treated with either CVVHDF (n=49) or CVVH (n=50) were analyzed.

Related Experiment Videos

  • Daily serum urea and creatinine levels were recorded for up to two weeks post-CRRT initiation.

    • Main Results:

    • The CVVH group exhibited significantly lower baseline urea and creatinine levels compared to the CVVHDF group.
    • These differences persisted and remained significant at 48 hours and throughout the treatment duration.
    • Mean urea and creatinine levels were consistently better controlled in patients treated with CVVH.

    Conclusions:

    • CRRT techniques significantly influence azotemic control.
    • Continuous veno-venous hemofiltration (CVVH) appears to provide superior control of urea and creatinine levels compared to CVVHDF in critically ill ARF patients.