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Updated: Sep 28, 2026

Catheter-based Endovascular Angioplasty for Fibrosing Mediastinitis-associated Pulmonary Vein Stenosis
Published on: August 26, 2025
Various reasons for repeat dilatation of stented pulmonary arteries in paediatric patients
M B E Schneider1, P Zartner, K Duveneck
1Department of Paediatric Cardiology, Charité Medical Centre, Humboldt University, Berlin, Germany. martin.schneider@charite.de
Insights
Repeat balloon angioplasty for pulmonary artery stenosis is often needed to accommodate patient growth. Other reasons include intimal proliferation and external compression, particularly in pediatric patients.
Area of Science:
- Pediatric Cardiology
- Interventional Cardiology
- Vascular Biology
Background:
- Pulmonary artery stenosis (PAS) is a significant challenge in pediatric cardiology.
- Balloon-expandable stents are used to treat PAS, but repeat interventions are sometimes necessary.
Purpose of the Study:
- To investigate the reasons for repeat interventions in patients with pulmonary artery stenosis treated with balloon-expandable stents.
- To analyze the time intervals between repeat interventions.
Main Methods:
- Retrospective observational study at a single pediatric cardiology center.
- Analysis of 38 patients (mean age 6.9 years) who underwent 46 stent implantations for pulmonary artery stenosis.
- Follow-up focused on stent adaptation to growth, pulmonary artery development, and right ventricle pressure gradients.
Main Results:
- 56 stents were implanted in 46 lesions.
- During a mean follow-up of 2.2 years, 40 repeat dilatations were performed on 28 stents.
- The mean time between stent implantation and repeat dilatation was 15.5 months.
Conclusions:
- Repeat dilatation is primarily performed to adjust stent diameter for patient growth.
- Other indications for repeat intervention include intimal proliferation (17.5%) and external compression (25%).
- Reasons for repeat interventions differ between pediatric and adult patients, with pediatric cases requiring interventions for diverse reasons.
Objective:
To evaluate the reasons for repeat intervention in patients treated with balloon expandable stents for pulmonary artery stenoses, with particular analysis of the time intervals between interventions.
Design:
A retrospective observational study.
Setting:
A single paediatric cardiology centre.
Patients:
38 patients, mean age 6.9 years, range 6 days to 34 years (one adult patient); mean weight 19.7 kg, range 2.5-75 kg.
Intervention:
Implantation of balloon expandable stents in 46 cases of main pulmonary artery stenosis, right pulmonary artery stenosis, left pulmonary artery stenosis, or right ventricle to pulmonary artery conduits.
Main Outcome Measures:
Adaptation of stent diameter to patient growth; development of pulmonary arteries; pressure gradient in the right ventricle.
Results:
56 stents were implanted in 46 lesions. During a mean follow up time of 2.2 years, 40 repeat dilatations were performed on 28 of 42 reinvestigated stents. A second repeat dilatation was performed on eight stents, and a third on four stents. The mean time period between implantation and repeat dilatations was 15.5 months.
Conclusions:
Repeat dilatation of stented pulmonary arteries was done mainly to adapt the stent diameter to the patient's growth. However, repeat dilatations were also performed to relieve stent obstruction caused by intimal proliferation (17.5%), or to overcome progressive external compression (25%). While most repeat interventions in adult patients are for intimal hyperplasia, in paediatric patients they are needed for a variety of reasons.
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