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Updated: Sep 28, 2026

Method of Studying Palatal Fusion using Static Organ Culture
Published on: September 19, 2015
[Simultaneous repair of complete cleft lip and palatein infancy-preliminary observation (271 cases report)]
Xihe Deng1, Ningxin Cheng, Hongtao Wang
1Guang-zhou Children's Hospital, Guangzhou Medical College, Guangzhou 510120, China.
Objective:
To Verify the safety and reliability of one-stage repair of complete cleft Lip and palate in infancy and to obtain the primary result.
Methods:
The simultaneous repair of complete cleft Lip and palate in infants 3 to 12 months of age were performed in 271 cases. The deformities include 185 cases of typical complete unilateral clefts and 75 cases of complete bilateral clefts, and other 11 atypical cleft infants. The preoperative orthopedic treatment for wide alveolar cleft was undertaken in 24 infants and the lip appearance and speech outcome were evaluated in 116 children by 1 to 4 years' postoperative follow-up.
Results:
All infants, except for dyspnea in 2 babies, palatal fistula formation in 6 cases and temporary wound hemorrhage in 5 infants, were recovered without complications. After orthopedic treatment, the width of the alveolar cleft was reduced 6.1 mm in average. The evaluation showed that 93.1% of children had got good or excellent lip appearance. And the acceptable or excellent speech was found in 94.8% children.
Conclusions:
Simultaneous repair of complete cleft lip and palate in infancy is safety and reliable. The preoperative orthopedic procedure is able to reduce the wide alveolar cleft and to achieve alignment of alveolar segments. The acceptable and or excellent lip appearance and speech function could be obtained in this one-stage operative procedure in infants.
