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[Effect of acute cold exposure on blood composition in rats treated with 6-Hydroxydopamine (author's transl)]
[Hokkaido Igaku Zasshi] the Hokkaido Journal of Medical Science
|May 1, 1975
Abstract:
Rats injected with 6-hydroxydopamine (6-OHDA) into the lateral ventricle showed greater elevation in plasma FFA and beta-hydroxybutyrate and significant decrease in blood sugar and lactate following acute cold exposure at -10 degrees C for 2 hours. Changes in the blood composition induced by the cold exposure in rats treated with 6-OHDA intravenously were not different from those observed in control rats. Adrenomedullectomized rats treated with 6-OHDA responded to the cold exposure with rather marked elevation in plasma FFA and beta-hydroxybutyrate. These results were discussed from the view-point of compensatory changes in metabolic regulation in the absence of norepinephrine.