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Published on: September 20, 2018

Bilateral presumed endogenous candida endophthalmitis and stage 3 retinopathy of prematurity

Luis C Gago1, Antonio Capone, Michael T Trese

  • 1Beaumont Eye Institute, William Beaumont Hospital, Royal Oak, Michigan, USA.

American Journal of Ophthalmology
|October 18, 2002
PubMed

Insights

This case report details a successful treatment of a premature infant with Candida endophthalmitis and retinopathy of prematurity. Prompt intervention led to favorable outcomes for both conditions.

Area of Science:

  • Ophthalmology
  • Neonatology
  • Infectious Diseases

Background:

  • Premature infants are susceptible to ocular infections and retinopathy.
  • Candida endophthalmitis and retinopathy of prematurity (ROP) can occur concurrently.
  • Combined ROP and endophthalmitis often have poor prognoses.

Purpose of the Study:

  • To present a case of endogenous bilateral Candida endophthalmitis in an infant with bilateral posterior stage 3 retinopathy of prematurity.
  • To highlight successful management of both conditions.

Main Methods:

  • Interventional case report.
  • Vitrectomy with intravitreal amphotericin B for Candida endophthalmitis.
  • Endolaser photocoagulation for stage 3 retinopathy of prematurity with "plus disease".

Main Results:

  • Successful eradication of Candida endophthalmitis in both eyes.
  • Regression of stage 3 retinopathy of prematurity in the right eye without ablation.
  • Successful management of stage 3 retinopathy with "plus disease" in the left eye.

Conclusions:

  • Prompt diagnosis and aggressive treatment are crucial for managing co-occurring Candida endophthalmitis and ROP.
  • Favorable anatomic outcomes are achievable even with severe presentations.
  • This case demonstrates a successful therapeutic approach for a challenging clinical scenario.
Abstract

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