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Albumin-coated knitted Dacron aortic prosthses. Study of postoperative inflammatory reactions
F A Kudo1, T Nishibe, K Miyazaki
1Department of Cardiovascular Surgery, Hokkaido University School of Medicine, Hokkaido, Japan.
Background:
The purpose of this study was to investigate the postoperative inflammatory reactions to albumin-coated Dacron grafts (ACGs), which are used in the repair of abdominal aortic aneurysm (AAA).
Experimental Design:
a retrospective study with a follow-up period of 14 days.
Setting:
University hospital.
Patients:
50 patients admitted for elective AAA repair from January 1997 to January 2000.
Interventions:
each patient underwent AAA repair with an ACG (Bard, albumin-coated Dacron graft).
Measures:
the white blood cell (WBC) count, plasma C-reactive protein (CRP) concentration, and body temperature (BT) were determined. The preoperative data, the highest values of the postoperative data, and the values 2 weeks postsurgery were analyzed.
Results:
The BT, CRP, and WBC increased and peaked at the 1st week postsurgery and then decreased gradually. The BT and WBC levels returned to normal within 2 weeks. The CRP level continued to show slightly elevated values in the 2nd week, but it was not significantly different compared to the preoperative data.
Conclusions:
The use of an albumin-impregnated prosthesis for the reconstruction of AAA is biocompatible, since no significant increases in inflammatory reactions are observed in the 2nd week postsurgery.
