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Functional computed tomography in oncology.

K A Miles1

  • 1Southernex Imaging and Queensland University of Technology, Department of Radiology, The Wesley Hospital, Chasely Street, Auchenflower, Australia. ken.miles@wesley.com.au

European Journal of Cancer (Oxford, England : 1990)
|October 22, 2002
PubMed
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Functional Computed Tomography (CT) uses conventional methods to assess tumor vasculature and angiogenesis. This technique aids in cancer diagnosis, staging, and therapy monitoring, offering significant clinical potential.

Area of Science:

  • Radiology
  • Oncology
  • Medical Imaging

Background:

  • Functional Computed Tomography (CT) leverages existing technologies and contrast agents.
  • It captures physiological parameters reflecting tumor and tissue vasculature.
  • These parameters serve as in-vivo markers of angiogenesis in tumors.

Purpose of the Study:

  • To highlight the capabilities and clinical applications of functional CT.
  • To emphasize its role in cancer diagnosis, staging, and therapy monitoring.
  • To discuss its potential impact on cancer patient imaging.

Main Methods:

  • Utilizes conventional CT scanners and contrast agents.
  • Incorporates specialized software for data analysis.
  • Focuses on capturing physiological parameters of tissue vasculature.

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Main Results:

  • Functional CT provides in-vivo markers of tumor angiogenesis.
  • It enables characterization of pulmonary nodules and detection of hepatic metastases.
  • It aids in grading cerebral gliomas and monitoring anti-angiogenesis therapies.

Conclusions:

  • Functional CT is a valuable research tool with broad clinical applications in oncology.
  • Advancements in software and multislice CT systems enhance its utility.
  • The technique is poised to significantly impact cancer imaging and patient management.