[Multiple calcified cerebral lesions, probably due to metastasis]

Area of Science:

• Neurology
• Oncology
• Radiology

Background:

• Metastases are a rare cause of cerebral calcifications due to rapid growth.
• This case examines unusual calcified cerebral lesions that prompted further investigation.

Observation:

• A 60-year-old woman presented with altered higher functions and neurological deficits.
• Brain imaging revealed calcified lesions with edema and mass effect, mimicking metastases.
• Thoracic imaging identified a spiculated lung lesion suggestive of primary lung cancer.

Findings:

• Cerebral calcifications with edema and enhancement can obscure metastatic origins.
• A spiculated lung lesion indicated a primary lung neoplasm as the likely cause.

Implications:

• Investigating the lungs is crucial for diagnosing the etiology of cerebral calcifications, even in the absence of respiratory symptoms.
• This case underscores the importance of comprehensive imaging in identifying primary tumors presenting with atypical neurological manifestations.