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Review article: bloating in functional bowel disorders.

S Zar1, M J Benson, D Kumar

  • 1OGEM Department, St George's Hospital Medical School, London, UK.

Alimentary Pharmacology & Therapeutics
|October 23, 2002
PubMed
Summary
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Bloating, a common functional bowel disorder symptom, is linked to measurable abdominal changes and potential bowel sensorimotor dysfunction. Current treatments are limited, necessitating research into novel therapies like probiotics and dietary changes.

Area of Science:

  • Gastroenterology
  • Functional Bowel Disorders

Background:

  • Bloating is a prevalent symptom in functional bowel disorders, often co-occurring with other issues but sometimes isolated.
  • Symptom severity typically escalates throughout the day and resolves overnight.
  • Contrary to being purely subjective, bloating is now recognized as correlating with objective increases in abdominal girth.

Purpose of the Study:

  • To explore the underlying pathophysiology of bloating in functional bowel disorders.
  • To identify potential mechanisms contributing to bloating.
  • To review current and future therapeutic strategies for bloating.

Main Methods:

  • Review of recent studies on bloating in functional bowel disorders.
  • Analysis of evidence supporting sensorimotor dysfunction.

Related Experiment Videos

  • Examination of potential contributing factors like gas, fluid, food intolerance, and gut microbiota.

    • Main Results:

    • Evidence suggests bloating is associated with measurable abdominal girth increases.
    • Bowel sensorimotor dysfunction is implicated as a key pathophysiological mechanism.
    • Pathways may involve abnormal gas/fluid retention, food intolerances, or altered gut flora.

    Conclusions:

    • The pathophysiology of bloating is complex and likely involves sensorimotor dysfunction, possibly segmental and transient.
    • Conventional treatments for functional bowel disorders are often ineffective for bloating.
    • Emerging therapies including dietary interventions, probiotics, hypnotherapy, and specific receptor-targeting drugs show promise.