Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Ocular perfusion abnormalities in diabetes.

Thomas A Ciulla1, Alon Harris, Paul Latkany

  • 1Midwest Eye Institute, Indianapolis, Indiana, USA.

Acta Ophthalmologica Scandinavica
|October 23, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prevalence of and risk factors for diabetic retinopathy: The Thessaloniki Eye Study.

Eye (London, England)·2026
Same author

The Future of Glaucoma: Data, AI, and Precision Medicine for Patient-Centered Care.

Journal of glaucoma·2026
Same author

Real-world integration of an autonomous artificial intelligence system for diabetic retinopathy screening in an endocrinology outpatient clinic.

The British journal of ophthalmology·2026
Same author

Stresses and fluid flow in lamina cribrosa through anisotropic poroelasticty.

ArXiv·2026
Same author

Stresses and fluid flow in lamina cribrosa through anisotropic poroelasticity.

Biomechanics and modeling in mechanobiology·2026
Same author

Gene therapy and cost-effectiveness analysis: Current issues and future research.

Med (New York, N.Y.)·2026
Same journal

Expression of interleukin-6, tumour necrosis factor-alpha and nitric oxides during episodes of ocular toxoplasmosis in an HIV patient.

Acta ophthalmologica Scandinavica·2007
Same journal

Varicella chorioretinitis.

Acta ophthalmologica Scandinavica·2007
Same journal

Pseudoexfoliation in the Reykjavik Eye Study: prevalence and related ophthalmological variables.

Acta ophthalmologica Scandinavica·2007
Same journal

Solving the enigma of exfoliation glaucoma: a breakthrough in glaucoma research.

Acta ophthalmologica Scandinavica·2007
Same journal

Incidence and prevalence of pseudoexfoliations and open-angle glaucoma in northern Sweden: II. Results after 21 years of follow-up.

Acta ophthalmologica Scandinavica·2007
Same journal

Incidence and prevalence of pseudoexfoliation and open-angle glaucoma in northern Sweden: I. Baseline report.

Acta ophthalmologica Scandinavica·2007
See all related articles

Diabetic retinopathy, a leading cause of blindness, involves ocular perfusion issues. Further research is needed to understand how high blood sugar damages eye blood vessels and to develop new therapies.

Area of Science:

  • Ophthalmology
  • Diabetology
  • Vascular Biology

Background:

  • Diabetic retinopathy is a major cause of irreversible blindness globally.
  • Ocular perfusion plays a critical role in the disease's pathophysiology.

Purpose of the Study:

  • To review the role of ocular perfusion in diabetic retinopathy.
  • To identify areas requiring further investigation in understanding the disease.

Main Methods:

  • A comprehensive Medline literature search was conducted.
  • The search covered English publications from 1966 to 2000.
  • Keywords focused on ocular perfusion and diabetic retinopathy.

Main Results:

  • Hyperglycemia induces diverse microvascular and macrovascular abnormalities.

Related Experiment Videos

  • Abnormal autoregulation is a key consequence of hyperglycemia.
  • Vascular dysfunction is linked to elevated glucose levels.

    • Conclusions:

    • Further research is essential to elucidate the mechanisms linking hyperglycemia to retinal vascular cell dysfunction.
    • Factors driving capillary dropout and angiogenesis, linked to hypoxia and increased perfusion, need delineation.
    • Understanding disease fundamentals will enable the development of targeted therapies to reverse or prevent pathological processes.