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[Serum uric acid in type 2 diabetic patients complicated by stroke]
Mei-Ping Guan1, Yao-Ming Xue, Jie Shen
1Department of Endocrinology, Nanfang Hospital, First Military Medical University, Guangzhou 510515, China.
Objective:
To investigate the association of hyperuricemia with the incidence of stroke in type 2 diabetic patients.
Methods:
Sixty type 2 diabetic patients with stroke, 75 patients with simple stoke and 67 simple type 2 diabetic patients were randomly selected from the hospitalized patients. The serum levels of uric acid (UA), total cholesterol (TC), triglyceride (TG), low-density lipoprotein-cholesterol(LDL), very-low-density lipoproteincholesterol (VLDL) and high-density lipoprotein- cholesterol (HDL) of all the patients were determined and comparison between the groups performed.
Results:
Male type 2 diabetic patients with stroke had significantly higher mean levels of serum uric acid than simple diabetic patients, but such patients of both genders all had lower HDL levels.
Conclusion:
The decreased serum HDL level poses as an important risk factor for stroke in all type 2 diabetic patients, among whom the male patients in particular have hyperuricemia as another important risk factor for stroke.