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Updated: Jul 8, 2026
10:19
Generation of Genetically Modified Mice through the Microinjection of Oocytes
Published on: June 15, 2017
[Techniques for producing transgenic animals and the recent development]
1Department of Histology and Embryology, First Military Medical University, Guangzhou 510515, China.
Di 1 Jun Yi Da Xue Xue Bao = Academic Journal of the First Medical College of PLA
|October 23, 2002
Summary
This review covers current methods for creating transgenic animals, including microinjection, viral vectors, and cell-based techniques. It also briefly discusses the future potential of these animal biotechnology approaches.
Area of Science:
- Animal Biotechnology
- Genetics
- Molecular Biology
Context:
- Transgenic animal production is crucial for research and development.
- Several established and emerging techniques exist for genetic modification of animals.
Purpose:
- To review and compare prevalent methods for generating transgenic animals.
- To provide a brief outlook on the future prospects of these techniques.
Summary:
- The article details techniques such as microinjection, retrovirus infection, embryonic stem cell manipulation, sperm-mediated gene transfer, and somatic cell nuclear transfer.
- Each method's application in creating genetically modified animals is discussed.
Impact:
- Provides a comprehensive overview of current transgenic animal production technologies.
- Informs researchers on the state-of-the-art and future directions in animal genetic engineering.
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