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[Folding of beta-hairpins]
1Institute of Protein Research, Russian Academy of Sciences, Pushchino, Moscow Region, 142290 Russia. ogalzit@vega.protres.ru
Molekuliarnaia Biologiia
|October 24, 2002
Abstract:
Identification of the factors governing the formation of beta-structure independently of the rest of the protein is important for understanding the folding process of protein into a unique native structure. It has been shown that some beta-hairpins can fold autonomously into native-like structures, either in aqueous solution or in the presence of an organic co-solvent. Our aim is to review recent theoretical and experimental studies of folding of beta-structures.