Related Experiment Video
Updated: Sep 28, 2026

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
Published on: January 11, 2020
Mild cognitive impairment--a review of prevalence, incidence and outcome according to current approaches
J Bischkopf1, A Busse, M C Angermeyer
1Department of Psychiatry, University of Leipzig, Leipzig, Germany. krausem@medizin.uni-leipzig.de
Objective:
Mild cognitive impairment is associated with an increased risk of developing dementia. However, agreement needs to be reached on clearly specified diagnostic criteria for mild cognitive impairment. The present paper critically reviews the different constructs of mild cognitive impairment on the basis of the available empirical evidence.
Method:
All published papers on mild cognitive impairment during the last 15 years on Medline and other databases were reviewed.
Results:
Age-specific prevalence and incidence rates according to the different constructs as well as the prognostic significance of the different constructs concerning the development of dementia are reported. Furthermore, a brief summary of recent research on possible risk factors for a negative course of mild cognitive impairment is provided.
Conclusion:
As there is no construct to date that pools all efforts of defining mild cognitive impairment, the review provides suggestions for an agreement on constructive terminology and research practice.
Insights
Diagnostic criteria for mild cognitive impairment (MCI) lack consensus, increasing dementia risk. This review examines MCI constructs, suggesting standardized terminology and research practices for better diagnosis and prognosis.
Area of Science:
- Neurology
- Geriatrics
- Cognitive Science
Background:
- Mild cognitive impairment (MCI) is a recognized risk factor for dementia.
- Current diagnostic criteria for MCI lack universal agreement.
- Standardized definitions are crucial for accurate diagnosis and prognosis.
Purpose of the Study:
- To critically review existing constructs of mild cognitive impairment (MCI).
- To evaluate the empirical evidence supporting different MCI definitions.
- To propose recommendations for standardized terminology and research practices.
Main Methods:
- Comprehensive literature search of Medline and other databases.
- Review focused on papers published within the last 15 years.
- Analysis of diagnostic criteria, prevalence, incidence, and prognostic significance.
Main Results:
- Prevalence and incidence rates vary significantly across different MCI constructs.
- The prognostic value of various MCI definitions regarding dementia development is reported.
- Recent research on risk factors for MCI progression is summarized.
Conclusions:
- No single construct currently unifies all efforts in defining MCI.
- The review advocates for an agreement on constructive terminology.
- Standardized research practices are recommended to improve MCI diagnosis and management.
More Related Videos
06:23The 4 Mountains Test: A Short Test of Spatial Memory with High Sensitivity for the Diagnosis of Pre-dementia Alzheimer's Disease
Published on: October 13, 2016
06:58Highlighting and Reducing the Impact of Negative Aging Stereotypes During Older Adults' Cognitive Testing
Published on: January 24, 2020
Related Concept Videos
Alzheimer's Disease: Overview
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ and tau...
Cognitive Development During Adulthood
Intellectual Disability
Dementia l: Introduction
Alzheimer Disease l: Introduction
Dementia
The progression of dementia is generally gradual.