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Updated: Aug 17, 2026
An Improved Mechanical Testing Method to Assess Bone-implant Anchorage
Published on: February 10, 2014
In vitro biomechanical studies of an anterior thoracolumbar implant
Patrick W Hitchon1, Matthew D Brenton, Hassan Serhan
1Department of Neurosurgery, University of Iowa, Iowa City, USA. patrick-hitchon@uiowa.edu
Abstract:
After L1 corpectomy in T11-L3 human cadaveric spine, anterior thoracolumbar instrumentation with strut grafting restores spinal stability. T12-L2 angular rotation was measured in response to moments of 0.0, 1.5, 3.0, 4.5, and 6.0 Nm in flexion, extension, lateral bending, and axial rotation, respectively. The spines were tested: 1) intact; 2) after partial L1 corpectomy, grafting, and instrumentation (Profile plate, DePuy-AcroMed, Raynham, MA), with the wooden dowel graft screwed to the plate; 3) without graft screw fixation; and 4) after flexion-extension cyclic fatiguing for 5000 cycles at a load of +/-3.0 Nm. Before and after fatiguing, the instrumented spine was significantly (p
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